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Despite encouraging preclinical findings, clinical data are currently absent, and prioritization of early-phase human trials is necessary before any definitive conclusions can be drawn
Long-term commitment to these changes is crucial for maintaining weight loss and preventing weight regain
Following the dose-optimization period, subjects continued on their optimized dose for the duration of the dose-maintenance period
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234-236 When people sleep in a new environment for the first time, they often experience the first night effect, which is a phenomenon characterized by overall poorer sleep quality and altered sleep architecture
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